Dermal reactivity to histamine, serotonin and bradykinin in relation to allergic skin reactions of the horse

Autor:	K. P. Baker, Alex Morrow, P. J. Quinn
Rok vydání:	1986
Předmět:	Pharmacology Hypersensitivity Immediate Serotonin General Veterinary Chemistry Hydrochloride Promethazine Hydrochloride Horse Bradykinin Intradermal Tests Ceratopogonidae Dermatitis Contact chemistry.chemical_compound Skin reaction Animals Reactivity (chemistry) Horse Diseases Horses Histamine
Zdroj:	Journal of veterinary pharmacology and therapeutics. 9(1)
ISSN:	0140-7783
Popis:	The reactivity of horse skin to intradermal inoculation of histamine, serotonin and bradykinin was investigated, and the resulting reactions compared with those produced in the same horses by a 1% whole-body extract of Cnliroides. Both histamine and bradykinin produced large reactions, but there was no significant correlation between the dermal responsiveness to insect allergen and either histamine or bradykinin. Two anti-hislamine drugs (promethazine hydrochloride and tripelennaniine hydrochloride) were effective in reducing the reaction produced by the insect extract.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2420dfceac21112083a1df02a4ac47d2 https://pubmed.ncbi.nlm.nih.gov/3701914 Zobrazit plný text záznamu Plný text