Hepatic and blood alterations in Lithobates catesbeianus tadpoles exposed to sulfamethoxazole and oxytetracycline
| Autor: | Camila Fatima, Rutkoski, Suelen Cristina, Grott, Nicole Grasmuk, Israel, Francisco Estevão, Carneiro, Fernando, de Campos Guerreiro, Sabrina, Santos, Priscila Aparecida, Horn, Amanda Alves, Trentini, Elizia, Barbosa da Silva, Claudia Almeida, Coelho de Albuquerque, Thiago Caique, Alves, Eduardo, Alves de Almeida |
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| Rok vydání: | 2022 |
| Předmět: |
Glutathione Peroxidase
Rana catesbeiana Environmental Engineering Sulfamethoxazole Superoxide Dismutase Health Toxicology and Mutagenesis Esterases Public Health Environmental and Occupational Health Oxytetracycline General Medicine General Chemistry Pollution Anti-Bacterial Agents Phosphates Glucose Liver Larva Animals Environmental Chemistry Biomarkers Water Pollutants Chemical Glutathione Transferase |
| Zdroj: | Chemosphere. 307:136215 |
| ISSN: | 0045-6535 |
| DOI: | 10.1016/j.chemosphere.2022.136215 |
| Popis: | In this study the effects of environmentally realistic concentrations of the antibiotics sulfamethoxazole (SMX) and oxytetracyclyne (OTC) on Lithobates catesbeianus tadpoles were evaluated, through the analyzes of the frequencies of micronucleus and nuclear abnormalities in erythrocytes, alterations in leucocytes, liver histopathology, and changes in hepatic esterase activities and oxidative stress biomarkers. The animals were exposed for 16 days at concentrations of 0 (control), 20, 90 and 460 ng L |
| Databáze: | OpenAIRE |
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