Do serum progesterone levels on day of embryo transfer influence pregnancy outcomes in artificial frozen-thaw cycles?
| Autor: | Cassandra Pakes, Michelle Volovsky, Genia Rozen, Alex Polyakov |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Pregnancy Rate medicine.medical_treatment Reproductive medicine Fertilization in Vitro Luteal phase Endometrium Letter to Editor Andrology Pregnancy Genetics medicine Humans Birth Rate Pregnancy outcomes Assisted Reproduction Technologies Genetics (clinical) Progesterone Retrospective Studies Cryopreservation Assisted reproductive technology business.industry Pregnancy Outcome Obstetrics and Gynecology Retrospective cohort study General Medicine Embryo Transfer Embryo transfer medicine.anatomical_structure Reproductive Medicine Female Live birth business Live Birth Developmental Biology |
| Zdroj: | J Assist Reprod Genet |
| Popis: | PURPOSE: The purpose of this study is to investigate whether progesterone (P4) levels on the day of frozen-thawed embryo transfer (FET) to a hormonally prepared endometrium correlate with pregnancy outcomes. METHODS: This is a large retrospective cohort analysis comprising of N = 2010 FETs. In these cycles, P4 levels on the day of transfer were assessed in relation to pregnancy outcomes. A threshold of 10 ng/mL was used to simulate currently accepted levels for physiological corpus luteal function. Biochemical pregnancy, clinical pregnancy, and live birth rates were compared between those with P4 levels above and below this threshold. Analyses using transfer day P4 thresholds of 5 ng/mL and 20 ng/mL were then completed to see if these could create further prognostic power. RESULTS: When comparing FET outcomes in relation to P4 levels |
| Databáze: | OpenAIRE |
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