Multispecies Machine Learning Predictions of In Vitro Intrinsic Clearance with Uncertainty Quantification Analyses

Autor:	Raquel Rodríguez-Pérez, Markus Trunzer, Nadine Schneider, Bernard Faller, Grégori Gerebtzoff
Rok vydání:	2022
Předmět:	Drug Discovery Pharmaceutical Science Molecular Medicine
Zdroj:	Molecular Pharmaceutics. 20:383-394
ISSN:	1543-8392 1543-8384
Popis:	In pharmaceutical research, compounds are optimized for metabolic stability to avoid a too fast elimination of the drug. Intrinsic clearance (CL
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241c4d76b720399e727161ab80fe61dd https://doi.org/10.1021/acs.molpharmaceut.2c00680 Zobrazit plný text záznamu