Blood Pressure Responses to Hypertension Treatment and Trends in Cognitive Function in Patients With Initially Difficult‐to‐Treat Hypertension: A Retrospective Subgroup Analysis of the Observational Study on Cognitive Function and SBP Reduction (OSCAR) Study
| Autor: | Jean-Pascal Berrou, Alexandra Konradi, Robert J. Petrella, Atul Pathak, Armand Sedefdjian, Evgeny Shlyakhto |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Systolic hypertension Endocrinology Diabetes and Metabolism Blood Pressure Angiotensin II Type 2 Receptor Blockers Thiophenes Cognition Internal medicine Internal Medicine medicine Humans Antihypertensive Agents Aged Retrospective Studies Intention-to-treat analysis business.industry Imidazoles Retrospective cohort study Eprosartan Middle Aged medicine.disease Original Papers Intention to Treat Analysis Pulse pressure Blood pressure Acrylates Hypertension Cohort Cardiology Female Cardiology and Cardiovascular Medicine business Body mass index medicine.drug |
| Zdroj: | J Clin Hypertens (Greenwich) |
| ISSN: | 1751-7176 1524-6175 |
| Popis: | J Clin Hypertens (Greenwich). 2012;14:78–84. ©2012 Wiley Periodicals, Inc. The Observational Study on Cognitive Function and SBP Reduction (OSCAR) provided opportunities to examine the influence of eprosartan on trends in cognitive performance in a large population of patients with difficult-to-treat hypertension (DTTH). A total of 4649 patients diagnosed retrospectively with DTTH, defined as systolic/diastolic blood pressure (SBP/DBP) ≥140/90 mm Hg despite use of at least 3 antihypertensive drugs during the month preceding the baseline visit comprised the intention-to-treat (ITT) cohort. The patients were given eprosartan-based antihypertension therapy (EBT; 600 mg/d). Blood pressure and cognitive function parameters included significant (P |
| Databáze: | OpenAIRE |
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