Predominant copper deficiency during prolonged enteral nutrition through a jejunostomy tube compared to that through a gastrostomy tube
| Autor: | Shinji Nishiwaki, Hiroo Hatakeyama, Motoshi Hayashi, Atsushi Tagami, Teruo Maeda, Masahide Iwashita, Jun Takada, Naoe Goto, Takahiko Asano, Takao Hayashi, Koshiro Saito |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty Neutropenia Time Factors Anemia Iron medicine.medical_treatment Jejunostomy Critical Care and Intensive Care Medicine Severity of Illness Index Enteral administration Gastroenterology Selenium Enteral Nutrition Percutaneous endoscopic gastrostomy Internal medicine medicine Humans Aged Enteral Tube Feeding Aged 80 and over Food Formulated Gastrostomy Cacao Nutrition and Dietetics business.industry Middle Aged medicine.disease Surgery Zinc Parenteral nutrition Seeds Female Copper deficiency business Copper |
| Zdroj: | Clinical Nutrition. 30:585-589 |
| ISSN: | 0261-5614 |
| DOI: | 10.1016/j.clnu.2011.04.008 |
| Popis: | Trace element deficiencies are known to occur during long-term enteral nutrition feeding. We compared the serum concentrations of trace elements between patients treated with gastrostomy and those treated with jejunostomy.Our subjects were 36 patients who underwent percutaneous endoscopic gastrostomy (PEG group) and 23 patients who underwent percutaneous endoscopic jejunostomy (PEJ group) and were maintained with enteral tube feeding for more than one year. The serum concentrations of copper, zinc, selenium, and iron were measured in the two groups. Clinical manifestations and the effectiveness of supplementation therapy against copper deficiency were also investigated.From 6 months after the onset of enteral feeding, the copper concentration of the PEJ group was significantly decreased compared with that of the PEG group (p0.001). There were no significant differences in the concentrations of zinc, selenium, or iron between the two groups. Severe copper deficiency was observed in 6 patients of the PEJ group and was accompanied with neutropenia and anemia. The copper deficiency was successfully treated in all of these patients by supplementation with 10-40 g of cocoa powder a day which was equivalent to a total daily dose of 1.36-2.56 mg of copper.Prolonged PEJ tube nutrition tends to result in copper deficiency, and cocoa supplementation is effective for treating such copper deficiency. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect