[Tumor volume in advanced gastric cancer as a prognostic factor correlating with lymph node involvement]
| Autor: | Milena Vukovic, Dejan Stevanovic, Ivan Pavlović, Dejan Radojevic, Dragan Radovanović, Nebojša Mitrović |
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| Rok vydání: | 2005 |
| Předmět: |
Oncology
Adult Male medicine.medical_specialty Prognostic factor Stomach Neoplasms Internal medicine medicine Carcinoma Humans Neoplasm Invasiveness Lymph node Aged Intestinal type business.industry Cancer General Medicine Advanced gastric cancer Middle Aged medicine.disease Prognosis medicine.anatomical_structure Lymphatic Metastasis Female Lymph Radiology business Volume (compression) |
| Zdroj: | Medicinski pregled. 58(7-8) |
| ISSN: | 0025-8105 |
| Popis: | Introduction It has been established that measurement of tumor volume, rather than its diameter, is a better indicator of the depth of tumor invasion and lymph node involvement. The present study evaluates the significance of tumor volume as a prognostic factor in gastric cancer. Material and methods This prospective clinical trail included 87 patients with gastric cancer admitted to Surgery Clinic "Dr. Dragisa Misovic" in Belgrade from 1998 to 2003. All patients were evaluated by standard diagnostic procedures, and after that underwent radical surgical treatment. Oncologic-surgical principles recommended by Japanese Research Society for Gastric Cancer were respected. Tumor volume was determined by measurement of specimens that had been obtained during surgery and by histopathological analysis. These criteria were analyzed and correlated with the lymph node status and clinicopathological factors. Results Single-factor analysis showed that lymph node metastases correlated with larger tumor diameter, larger tumor volume, depth of tumor invasion, diffuse and low-grade differentiation of the intestinal type of gastric carcinoma. Using a linear correlation coefficient, it was found that there was a highly significant correlation of tumor volume and number of metastatic nodes in groups between lymph nodes r=0.567; p |
| Databáze: | OpenAIRE |
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