Prevalence, comorbidity, and risk factors for functional bowel symptoms: a population-based survey in Northern Norway
| Autor: | Eyvind J. Paulssen, Jon Florholmen, Bjørn Straume, Anne Mette Asfeldt, Ragnar K. Breckan |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Constipation Health Status Comorbidity Irritable Bowel Syndrome Musculoskeletal Pain Risk Factors Surveys and Questionnaires Adaptation Psychological Prevalence Palpitations Flatulence Young adult Irritable bowel syndrome media_common Aged 80 and over education.field_of_study biology Depression Norway Age Factors Headache Gastroenterology Middle Aged Feeling Female medicine.symptom Adult Diarrhea medicine.medical_specialty Adolescent media_common.quotation_subject Population Dizziness Helicobacter Infections Young Adult Sex Factors Internal medicine medicine Humans education Aged Helicobacter pylori business.industry biology.organism_classification medicine.disease Health Surveys Dyssomnias Abdominal Pain Physical therapy business Stress Psychological |
| Zdroj: | Scandinavian Journal of Gastroenterology. 47:1274-1282 |
| ISSN: | 1502-7708 0036-5521 |
| DOI: | 10.3109/00365521.2012.688215 |
| Popis: | To assess the occurrence of functional bowel (FB) symptoms in Northern Norway, and to describe gender differences, comorbidity, and association to risk factors, including Helicobacter pylori infection.Adult subjects (18-85 years) from the communities Bodø and Sørreisa were invited to complete a questionnaire on gastrointestinal symptoms, and to provide stool samples for assessment of H. pylori.Of 3927 invited subjects, 1731 (44.1%) responded to the questionnaire and 1416 (36.0%) provided stool samples. Functional bowel symptoms were found in 25%, somewhat more frequent in females (28.6%). Symptom pattern differed between genders only with regard to constipation. Presence of FB symptoms was significantly associated with gastroesophageal reflux symptoms, headache, dizziness, palpitations, sleep disturbances, and musculoskeletal symptoms. Psychometric traits were also more prevalent: feeling of low coping ability, feeling depressed, feeling of time pressure, and a low self-evaluation of health. In a multivariate regression model, factors that influenced the reporting FB symptoms were male gender (OR 0.71, 95% CI (0.52; 0.96)), age 50-69 years or ≥70 years (OR 0.49 (0.30; 0.80) and 0.40 (0.21; 0.79)), obesity (OR 1.61 (1.05; 2.47)), NSAID use (OR 2.50 (1.63; 3.83)), and previous abdominal surgery (OR 1.54 (1.05; 2.26)). The presence of H. pylori was not associated with FB symptoms.Functional bowel symptoms are prevalent, but our findings may be prone to self-selection bias. FB symptoms carry a significant burden of comorbidity. Female gender and low age are known risk factors for FB symptoms, whereas NSAID use as a risk factor deserves further clarification. |
| Databáze: | OpenAIRE |
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