Primary retroperitoneal liposarcoma: Clinical and histological analysis of ten cases
| Autor: | Yolanda Rodríguez-Gil, Francisco Colina-Ruizdelgado, Enrique Moreno-González, Mario Fernández-Ruiz, Alejandro Manrique-Municio, Juan Manuel Guerra-Vales |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Breast Neoplasms Kaplan-Meier Estimate Abdominal cavity Malignancy Complete resection Disease-Free Survival Resection Neoplasms Multiple Primary Palpable abdominal mass medicine Round cell Humans Retroperitoneal liposarcoma Retroperitoneal Neoplasms Aged Retrospective Studies Aged 80 and over Incidental Findings Hepatology business.industry Gastroenterology Liposarcoma Middle Aged medicine.disease Liposarcoma Myxoid Surgery medicine.anatomical_structure Spain Abdominal Neoplasms Concomitant Female Neoplasm Recurrence Local business |
| Zdroj: | Gastroenterología y Hepatología. 33:370-376 |
| ISSN: | 0210-5705 |
| Popis: | Retroperitoneal liposarcoma constitutes an uncommon and locally aggressive malignancy. We performed a retrospective analysis of 10 patients (6 males; mean age: 63.2+/-11 years) with histologically proven retroperitoneal liposarcoma seen at our institution between 1999 and 2007. Presence of a palpable abdominal mass was the main symptom at diagnosis. All patients underwent complete surgical resection. Negative microscopic margin was achieved in four cases. Histological analysis revealed the following subtypes: well-differentiated (6 cases), dedifferentiated (two cases), pleomorphic, and myxoid/round cell (one case each). Concomitant resection of adjacent organs was needed in five cases. Half of the patients developed tumor recurrence, mainly limited to the retroperitoneum or abdominal cavity. The mean recurrence-free survival was 43.3 months (95%CI: 25.7-60.8), with 3- and 5-year overall survival rates of 79% and 61%, respectively. Patients undergoing complete resection with clear margins showed a near-significant trend toward increased recurrence-free survival (62.9 vs. 29.3 months; P=0.06). |
| Databáze: | OpenAIRE |
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