Mondini dysplasia and congenital cytomegalovirus infection
| Autor: | James F. Bale, Bruce J. Gantz, David B. Wexler, Linda J. Kirby-Keyser, Nancy M. Bauman, Kenneth D. Dolan, Brian F. McCabe |
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| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty Hearing loss Hearing Loss Sensorineural Congenital cytomegalovirus infection Temporal bone otorhinolaryngologic diseases medicine Humans Child business.industry Infant Temporal Bone Anatomy medicine.disease Surgery Cochlea medicine.anatomical_structure Dysplasia Pediatrics Perinatology and Child Health Cytomegalovirus Infections Mondini dysplasia Cochlear aqueduct Sensorineural hearing loss Female sense organs Vestibule Labyrinth medicine.symptom business Tomography X-Ray Computed Enlarged vestibular aqueduct |
| Zdroj: | The Journal of pediatrics. 124(1) |
| ISSN: | 0022-3476 |
| Popis: | We report a case of bilateral temporal bone anomalies in a child with symptomatic congenital cytomegalovirus infection and severe, bilateral sensorineural hearing loss identified at 3 months of age. High-resolution temporal bone computed tomography (HRCT) revealed bilateral findings of a short, malformed cochlea lacking an interscalar septum, a short and wide internal auditory canal, and an enlarged vestibular aqueduct, features diagnostic of bilateral Mondini dysplasia. To determine the importance of this observation, we completed HRCT in five additional children between 7 months and 9 years of age who had evidence of symptomatic congenital cytomegalovirus infection. One child with profound sensorineural hearing loss had severe bilateral temporal bone dysplasia with a small cochlea lacking an interscalar septum, an abnormal vestibule, and a large cochlear aqueduct. Of the remaining four children, hearing thresholds ranged from normal to profoundly decreased, but their HRCT scans were normal to visual inspection. When inner ear dimensions of these temporal bones were compared with norms established by Pappas and coworkers, however, seven of the eight ears had short cochleas and narrow lateral semicircular canals, and three ears had short or narrow vestibules. These results indicate that congenital cytomegalovirus infection may cause anomalies or growth disturbances of the temporal bone. |
| Databáze: | OpenAIRE |
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