Sars-CoV-2 in pregnancy: Why is it better than expected?
| Autor: | Arsène Mekinian, Tullio Ghi, Leonardo Calza, Tiziana Frusca, Elvira Di Pasquo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Sars-CoV-2
Immunology Pneumonia Viral Better than Expected Disease medicine.disease_cause Article Pathogenesis Betacoronavirus Blunt Pregnancy Pandemic Obstetrics and Gynaecology Medicine Humans Pregnancy Complications Infectious Pandemics Coronavirus Inflammation business.industry Obstetrics and Gynecology Outbreak COVID-19 medicine.disease Reproductive Medicine Cytokines Female business Coronavirus Infections |
| Zdroj: | European Journal of Obstetrics, Gynecology, and Reproductive Biology European Journal of Obstetrics & Gynecology and Reproductive Biology |
| ISSN: | 1872-7654 0301-2115 |
| Popis: | Since the outbreak of Coronavirus disease in December 2019, information specific to pregnancy remains limited and controversial. Based on data from previous reports, it has been noticed that contrary to prior pandemics such as SARS, MERS and H1N1 and although pregnancy is usually considered as a condition of high susceptibility to viral infections, new SARS-CoV2 infection seems to have a more benign clinical course when affecting pregnant women. We speculate that during pregnancy the physiological "silencing" of the Th1 pro-inflammatory response may blunt the cytokines storm which is thought to play a key-role in the pathogenesis of the severe complications of Covid-19. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect