Laboratory surveillance of antimicrobial resistance and multidrug resistance among Streptococcus pneumoniae isolated in the Kinki region of Japan, 2001-2015
| Autor: | Yuji Tanaka, Masanobu Oohama, Tamaki Orita, Machiko Kita, Tamotsu Ono, Tomomi Kofuku, Takefumi Higuchi, Yasunao Wada, Takuya Maede, Katsutoshi Yamasaki, Toshinori Kamisako, Isao Nishi, Tatsuya Nakamura, Hisaaki Nishio, Saori Fukuda, Yoshie Hikita, Takumi Jikimoto, Masaru Komatsu, Hirofumi Toda, Kaori Satoh, Noriyuki Sueyoshi, Isako Nakai, Koichi Shimakawa, Kaneyuki Kida, Kunihiko Moro, Toru Tobe, Masahiro Toyokawa, Masahiro Akagi |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Adult Carbapenem Heptavalent Pneumococcal Conjugate Vaccine medicine.drug_class 030106 microbiology Cephalosporin Antibiotics Penicillins complex mixtures Pneumococcal conjugate vaccine Pneumococcal Infections Microbiology 03 medical and health sciences Antibiotic resistance stomatognathic system Japan Drug Resistance Multiple Bacterial polycyclic compounds medicine Humans Pharmacology (medical) Child Cephalosporin Resistance Retrospective Studies business.industry Cephalosporins Penicillin Multiple drug resistance Infectious Diseases Streptococcus pneumoniae Carbapenems Epidemiological Monitoring Macrolides business medicine.drug |
| Zdroj: | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 24(3) |
| ISSN: | 1437-7780 |
| Popis: | The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced among children in Japan in 2010. There are no long-term multicenter surveillance studies of antimicrobial resistance in S. pneumoniae before and after the introduction of PCV7. Therefore, we examined chronological trends in antimicrobial resistance among 4534 strains of S. pneumoniae isolated from both children and adults in the Kinki region of Japan during 2001–2015. High-level penicillin and third-generation cephalosporin resistance in S. pneumoniae increased among both children and adults during the period before the introduction of PCV7 (2001–2010). Besides penicillin and cephalosporin, pneumococcal carbapenem and macrolide resistance increased among children. The rate of resistance to these antibiotics was higher among children than among adults. The introduction of PCV7 decreased the rate of non-susceptibility to β-lactam antibiotics and the rate of multidrug resistant S. pneumoniae among children, but not among adults. |
| Databáze: | OpenAIRE |
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