Toxic acute hepatitis and hepatic fibrosis after consumption of chaparral tablets
| Autor: | H. Mäkisalo, H. Autio-Harmainen, Juhani Lehtola, H. Kauma, Krister Höckerstedt, R. Koskela |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Toxic hepatitis
Adult Liver Cirrhosis medicine.medical_specialty Pathology Gastroenterology Fibrosis Internal medicine medicine Humans Hepatitis geography geography.geographical_feature_category medicine.diagnostic_test business.industry medicine.disease Chaparral Larrea Liver Liver biopsy Female Plant Preparations medicine.symptom Chemical and Drug Induced Liver Injury Hepatic fibrosis business Liver function tests Acute hepatitis Phytotherapy |
| Zdroj: | Scandinavian journal of gastroenterology. 39(11) |
| ISSN: | 0036-5521 |
| Popis: | In this report we describe a young, previously healthy woman who developed severe acute hepatitis after consumption of chaparral tablets, a commonly used herbal product. In this case, the elimination-rechallenge event and the exclusion of other possible aetiologic factors strongly supported true causality between the herbal product and the liver damage. Primary liver biopsy showed severe toxic hepatitis consistent with previous reports of chaparral-induced liver damage. Later, 6 months after the liver function tests had normalized, permanent hepatic fibrosis could still be seen. |
| Databáze: | OpenAIRE |
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