Obstetric Outcomes of SARS-CoV-2 Infection in Asymptomatic Pregnant Women

Autor: Cruz-Lemini, Monica, Ferriols Perez, Elena, de la Cruz Conty, Maria Luisa, Cano Aguilar, Africa, Encinas Pardilla, Maria Begona, Prats Rodriguez, Pilar, Muner Hernando, Marta, Forcen Acebal, Laura, Pintado Recarte, Pilar, Medina Mallen, Maria del Carmen, Perez Perez, Noelia, Canet Rodriguez, Judit, Villalba Yarza, Ana, Nieto Velasco, Olga, del Barrio Fernandez, Pablo Guillermo, Orizales Lago, Carmen Maria, Marcos Puig, Beatriz, Munoz Abellana, Begona, Fuentes Ricoy, Laura, Rodriguez Vicente, Agueda, Janeiro Freire, Maria Jesus, Alferez Alvarez-Mallo, Macarena, Casanova Pedraz, Cristina, Alomar Mateu, Onofre, Lesmes Heredia, Cristina, Wizner de Alva, Juan Carlos, Posadas San Juan, Alma, Macia Badia, Montserrat, Alvarez Colomo, Cristina, Sanchez Munoz, Antonio, Pratcorona Alicart, Laia, Alonso Saiz, Ruben, Lopez Rodriguez, Monica, Barbancho Lopez, Maria Carmen, Meca Casbas, Marta Ruth, Vaquerizo Ruiz, Oscar, Moran Antolin, Eva, Nunez Valera, Maria Jose, Fernandez Fernandez, Camino, Tubau Navarra, Albert, Cano Garcia, Alejandra Maria, Soldevilla Perez, Susana, Gattaca Abasolo, Irene, Adanez Garcia, Jose, Puertas Prieto, Alberto, Ostos Serna, Rosa, Guadix Martin, Maria del Pilar, Catalina Coello, Monica, Espuelas Malon, Silvia, Sainz Bueno, Jose Antonio, Granell Escobar, Maria Reyes, Cruz Melguizo, Sara, Martinez Perez, Oscar, Spanish Obstetric Emergency Grp
Přispěvatelé: Universidad de Sevilla. Departamento de Cirugía, Institut Català de la Salut, [Cruz-Lemini M] Department of Gynecology and Obstetrics, Women and Perinatal Health Research Group, Biomedical Research Institute (IIB-Sant Pau), Santa Creu i Sant Pau University Hospital, Barcelona, Spain. [Ferriols Perez E] Department of Gynecology and Obstetrics, Parc de Salut Mar University Hospital, Barcelona, Spain. [de la Cruz Conty ML] Fundacion de Investigacion Biomedica, Puerta de Hierro University Hospital of Majadahonda, Madrid, Spain. [Caño Aguilar A] Department of Gynecology and Obstetrics, San Cecilio University Hospital of Granada, Granada, Spain. [Encinas Pardilla MB] Department of Gynecology and Obstetrics, Puerta de Hierro University Hospital of Majadahonda, Madrid, Spain. [Prats Rodríguez P] Department of Gynecology and Obstetrics, Dexeus University Hospital, Barcelona, Spain. [Rodriguez Vicente A] Departament de Ginecologia i Obstetricia, Hospital Universitari de Girona Dr. Josep Trueta, Institut Català de la Salut (ICS), Girona, Spain, Hospital Universitari de Girona Dr Josep Trueta, UAM. Departamento de Obstetricia y Ginecología
Jazyk: angličtina
Rok vydání: 2021
Předmět:
embarazo
Embaràs
Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproduction::Pregnancy [PHENOMENA AND PROCESSES]
humanos
lcsh:QR1-502
coronavirus
adolescente
Maternal complications
COVID-19 (Malaltia)
lcsh:Microbiology
0302 clinical medicine
fenómenos fisiológicos reproductivos y urinarios::fenómenos fisiológicos de la reproducción::reproducción::embarazo [FENÓMENOS Y PROCESOS]
Pregnancy
estudios prospectivos
virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES]
Rupture of membranes
Childbirth
030212 general & internal medicine
Prospective Studies
Young adult
Pregnancy Complications
Infectious

Prospective cohort study
Asymptomatic Infections
mediana edad
030219 obstetrics & reproductive medicine
Obstetrics
Asymptomatic infection
Pregnancy Outcome
afecciones patológicas
signos y síntomas::procesos patológicos::atributos de la enfermedad::enfermedades asintomáticas::infecciones asintomáticas [ENFERMEDADES]

Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES]
Perinatal outcomes
Middle Aged
adulto
adulto joven
Infectious Diseases
infecciones asintomáticas
perinatal outcomes
Female
medicine.symptom
delivery
Delivery
resultado del embarazo
Adult
medicine.medical_specialty
Pathological Conditions
Signs and Symptoms::Pathologic Processes::Disease Attributes::Asymptomatic Diseases::Asymptomatic Infections [DISEASES]

Adolescent
Medicina
SARS-CoV-2
asymptomatic infection
coronavirus
delivery
maternal complications
perinatal outcomes
pregnancy

Asymptomatic
Article
03 medical and health sciences
Young Adult
Virology
medicine
maternal complications
Humans
complicaciones del embarazo
análisis multifactorial
asymptomatic infection
lactante
business.industry
SARS-CoV-2
Infant
Newborn

COVID-19
Infant
Odds ratio
medicine.disease
Confidence interval
Coronavirus
Pregnancy Complications
Spain
Multivariate Analysis
Pregnant Women
business
Zdroj: Viruses, Vol 13, Iss 112, p 112 (2021)
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Scientia
Viruses
Viruses-Basel
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Volume 13
Issue 1
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
VIRUSES-BASEL
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Biblos-e Archivo. Repositorio Institucional de la UAM
idUS. Depósito de Investigación de la Universidad de Sevilla
ISSN: 1999-4915
Popis: Artículo con numerosos autores. Sólo destacamos el primero. el de la UAM y el Grupo colectivo
Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13–3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms
This project was supported by public funds obtained in competitive calls: Grant COV20/00021 (EUR 43,000 from the Instituto de Salud Carlos III—Spanish Ministry of Health and co-financed with Fondo Europeo de Desarrollo Regional (FEDER) funds. Dr Cruz-Lemini is supported by a Juan Rodés contract JR19/00047, Instituto de Salud Carlos III—Spanish Ministry of Health
Databáze: OpenAIRE