Obstetric Outcomes of SARS-CoV-2 Infection in Asymptomatic Pregnant Women
Autor: | Cruz-Lemini, Monica, Ferriols Perez, Elena, de la Cruz Conty, Maria Luisa, Cano Aguilar, Africa, Encinas Pardilla, Maria Begona, Prats Rodriguez, Pilar, Muner Hernando, Marta, Forcen Acebal, Laura, Pintado Recarte, Pilar, Medina Mallen, Maria del Carmen, Perez Perez, Noelia, Canet Rodriguez, Judit, Villalba Yarza, Ana, Nieto Velasco, Olga, del Barrio Fernandez, Pablo Guillermo, Orizales Lago, Carmen Maria, Marcos Puig, Beatriz, Munoz Abellana, Begona, Fuentes Ricoy, Laura, Rodriguez Vicente, Agueda, Janeiro Freire, Maria Jesus, Alferez Alvarez-Mallo, Macarena, Casanova Pedraz, Cristina, Alomar Mateu, Onofre, Lesmes Heredia, Cristina, Wizner de Alva, Juan Carlos, Posadas San Juan, Alma, Macia Badia, Montserrat, Alvarez Colomo, Cristina, Sanchez Munoz, Antonio, Pratcorona Alicart, Laia, Alonso Saiz, Ruben, Lopez Rodriguez, Monica, Barbancho Lopez, Maria Carmen, Meca Casbas, Marta Ruth, Vaquerizo Ruiz, Oscar, Moran Antolin, Eva, Nunez Valera, Maria Jose, Fernandez Fernandez, Camino, Tubau Navarra, Albert, Cano Garcia, Alejandra Maria, Soldevilla Perez, Susana, Gattaca Abasolo, Irene, Adanez Garcia, Jose, Puertas Prieto, Alberto, Ostos Serna, Rosa, Guadix Martin, Maria del Pilar, Catalina Coello, Monica, Espuelas Malon, Silvia, Sainz Bueno, Jose Antonio, Granell Escobar, Maria Reyes, Cruz Melguizo, Sara, Martinez Perez, Oscar, Spanish Obstetric Emergency Grp |
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Přispěvatelé: | Universidad de Sevilla. Departamento de Cirugía, Institut Català de la Salut, [Cruz-Lemini M] Department of Gynecology and Obstetrics, Women and Perinatal Health Research Group, Biomedical Research Institute (IIB-Sant Pau), Santa Creu i Sant Pau University Hospital, Barcelona, Spain. [Ferriols Perez E] Department of Gynecology and Obstetrics, Parc de Salut Mar University Hospital, Barcelona, Spain. [de la Cruz Conty ML] Fundacion de Investigacion Biomedica, Puerta de Hierro University Hospital of Majadahonda, Madrid, Spain. [Caño Aguilar A] Department of Gynecology and Obstetrics, San Cecilio University Hospital of Granada, Granada, Spain. [Encinas Pardilla MB] Department of Gynecology and Obstetrics, Puerta de Hierro University Hospital of Majadahonda, Madrid, Spain. [Prats Rodríguez P] Department of Gynecology and Obstetrics, Dexeus University Hospital, Barcelona, Spain. [Rodriguez Vicente A] Departament de Ginecologia i Obstetricia, Hospital Universitari de Girona Dr. Josep Trueta, Institut Català de la Salut (ICS), Girona, Spain, Hospital Universitari de Girona Dr Josep Trueta, UAM. Departamento de Obstetricia y Ginecología |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
embarazo
Embaràs Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproduction::Pregnancy [PHENOMENA AND PROCESSES] humanos lcsh:QR1-502 coronavirus adolescente Maternal complications COVID-19 (Malaltia) lcsh:Microbiology 0302 clinical medicine fenómenos fisiológicos reproductivos y urinarios::fenómenos fisiológicos de la reproducción::reproducción::embarazo [FENÓMENOS Y PROCESOS] Pregnancy estudios prospectivos virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES] Rupture of membranes Childbirth 030212 general & internal medicine Prospective Studies Young adult Pregnancy Complications Infectious Prospective cohort study Asymptomatic Infections mediana edad 030219 obstetrics & reproductive medicine Obstetrics Asymptomatic infection Pregnancy Outcome afecciones patológicas signos y síntomas::procesos patológicos::atributos de la enfermedad::enfermedades asintomáticas::infecciones asintomáticas [ENFERMEDADES] Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES] Perinatal outcomes Middle Aged adulto adulto joven Infectious Diseases infecciones asintomáticas perinatal outcomes Female medicine.symptom delivery Delivery resultado del embarazo Adult medicine.medical_specialty Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Asymptomatic Diseases::Asymptomatic Infections [DISEASES] Adolescent Medicina SARS-CoV-2 asymptomatic infection coronavirus delivery maternal complications perinatal outcomes pregnancy Asymptomatic Article 03 medical and health sciences Young Adult Virology medicine maternal complications Humans complicaciones del embarazo análisis multifactorial asymptomatic infection lactante business.industry SARS-CoV-2 Infant Newborn COVID-19 Infant Odds ratio medicine.disease Confidence interval Coronavirus Pregnancy Complications Spain Multivariate Analysis Pregnant Women business |
Zdroj: | Viruses, Vol 13, Iss 112, p 112 (2021) idUS: Depósito de Investigación de la Universidad de Sevilla Universidad de Sevilla (US) Scientia Viruses Viruses-Basel r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname Volume 13 Issue 1 r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe VIRUSES-BASEL r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol Biblos-e Archivo. Repositorio Institucional de la UAM idUS. Depósito de Investigación de la Universidad de Sevilla |
ISSN: | 1999-4915 |
Popis: | Artículo con numerosos autores. Sólo destacamos el primero. el de la UAM y el Grupo colectivo Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13–3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms This project was supported by public funds obtained in competitive calls: Grant COV20/00021 (EUR 43,000 from the Instituto de Salud Carlos III—Spanish Ministry of Health and co-financed with Fondo Europeo de Desarrollo Regional (FEDER) funds. Dr Cruz-Lemini is supported by a Juan Rodés contract JR19/00047, Instituto de Salud Carlos III—Spanish Ministry of Health |
Databáze: | OpenAIRE |
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