Marine Pharmacology in 2016–2017: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action
| Autor: | Fumiaki Nakamura, Orazio Taglialatela-Scafati, Abimael D. Rodríguez, Alejandro M. S. Mayer, Aimee J Guerrero, Nobuhiro Fusetani |
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| Přispěvatelé: | Mayer, Alejandro M S, Guerrero, Aimee J, Rodríguez, Abimael D, Taglialatela-Scafati, Orazio, Nakamura, Fumiaki, Fusetani, Nobuhiro |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Drug
Antifungal Aquatic Organisms natural product Antifungal Agents sea chemical medicine.drug_class media_common.quotation_subject Anti-Inflammatory Agents Antiprotozoal Agents Antitubercular Agents Pharmaceutical Science Review Pharmacology Antiviral Agents Nervous System Anti-inflammatory chemistry.chemical_compound Immune system Drug Discovery preclinical medicine Animals Humans Hypoglycemic Agents Pharmacological and Toxicological Phenomena pharmaceutical Pharmacology Toxicology and Pharmaceutics (miscellaneous) lcsh:QH301-705.5 media_common Biological Products Natural product business.industry pipeline drug marine Anti-Bacterial Agents chemistry lcsh:Biology (General) Immune System Antiprotozoal pharmacology business toxicology |
| Zdroj: | Marine Drugs, Vol 19, Iss 49, p 49 (2021) Marine Drugs |
| ISSN: | 1660-3397 |
| Popis: | The review of the 2016–2017 marine pharmacology literature was prepared in a manner similar as the 10 prior reviews of this series. Preclinical marine pharmacology research during 2016–2017 assessed 313 marine compounds with novel pharmacology reported by a growing number of investigators from 54 countries. The peer-reviewed literature reported antibacterial, antifungal, antiprotozoal, antituberculosis, and antiviral activities for 123 marine natural products, 111 marine compounds with antidiabetic and anti-inflammatory activities as well as affecting the immune and nervous system, while in contrast 79 marine compounds displayed miscellaneous mechanisms of action which upon further investigation may contribute to several pharmacological classes. Therefore, in 2016–2017, the preclinical marine natural product pharmacology pipeline generated both novel pharmacology as well as potentially new lead compounds for the growing clinical marine pharmaceutical pipeline, and thus sustained with its contributions the global research for novel and effective therapeutic strategies for multiple disease categories. |
| Databáze: | OpenAIRE |
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