Evaluation of and additional data on an improved simple charcoal method to determine oestrogen receptors
| Autor: | J. P. Persijn, C. B. Korsten |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Electrophoresis
medicine.medical_specialty Time Factors Chemistry Biochemistry (medical) Clinical Biochemistry education Uterus Breast Neoplasms General Medicine medicine.anatomical_structure Endocrinology Receptors Estrogen Internal medicine Charcoal medicine Methods Humans Female Oestrogen receptor Receptor Human breast |
| Zdroj: | Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie. 15(5) |
| ISSN: | 0340-076X 1235-1245 |
| Popis: | Additional information and some modifications of an earlier published method ((1972) Z. Klin. Chem. Klin. Biochem., 10, 502-508) for the assay of oestrogen receptor in human breast tumours are presented. The correlation between the results obtained with this method and with the electrophoresis procedure of Wagner ((1972) Hopper Seyler's Z. Physiol. Chem., 353, 1235-1245) was found to be good. The use of glycerol stabilized calf uterus extract for quality control is proposed. Various factors affecting the assay and the discrimination between receptor positive and receptor negative are critically discussed. |
| Databáze: | OpenAIRE |
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