Individual and household correlates of Helicobacter pylori infection among Young Ethiopian children in Ziway, Central Ethiopia
| Autor: | Mehret Tesfaye, Aster Tsegaye, Sosina Walelign, Hannah Spotts, Caroline Correia, Kayla Schacher, Bineyam Taye, Kassu Desta |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Logistic regression Helicobacter Infections Odds lcsh:Infectious and parasitic diseases Feces 03 medical and health sciences 0302 clinical medicine Medical microbiology Surveys and Questionnaires Prevalence Humans Medicine lcsh:RC109-216 030212 general & internal medicine Child Socioeconomic status Children Family Characteristics Univariate analysis Helicobacter pylori biology business.industry Transmission (medicine) Confounding biology.organism_classification Cross-Sectional Studies Logistic Models Infectious Diseases Socioeconomic Factors Risk factors Child Preschool Female 030211 gastroenterology & hepatology Ethiopia business H. pylori Research Article Demography |
| Zdroj: | BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020) BMC Infectious Diseases |
| ISSN: | 1471-2334 |
| DOI: | 10.1186/s12879-020-05043-1 |
| Popis: | Background Investigating distinct individual- and household-level risk factors for acquiring Helicobacter pylori (H. pylori) infection can inform disease prevention efforts and implicate possible routes of transmission. This study determined the magnitude of H. pylori infection among schoolchildren in Ziway, central Ethiopia and identified personal and household correlates of H. pylori infection in young Ethiopian children. Methods A total of 434 schoolchildren participated in this cross-sectional study. Infection status was assessed using antigen and antibody rapid tests. Demographic and lifestyle information was obtained from parents via an interviewer-led questionnaire. Univariate and multivariate logistic regressions were performed to assess the relationships between potential individual- and household-level risk factors and H. pylori infection. Results The prevalence of H. pylori infection was 65.7% (285/434). Of the personal variables assessed, the age group 10–14 years was found to be significantly associated with higher odds of H. pylori infection in univariate analysis (COR = 2.22, 95% CI: 1.06–4.66, p = 0.03) and remained positively correlated after adjusting for confounding factors. Of the household-level factors explored, having a traditional pit or no toilet was found to be significantly associated with 3.93-fold higher odds of H. pylori infection (AOR = 3.93, 95% CI: 1.51–10.3, p = 0.01), while the presence of smokers in the household was associated with 68% lower odds of infection (AOR = 0.32, 95% CI: 0.11–0.89, p = 0.03). Conclusion This study from a developing country provides additional evidence for older age as a personal risk factor for H. pylori infection and identifies correlations between socioeconomic and sanitation household factors and positive childhood infection status. The associations reported here support the hypothesized fecal-oralroute of transmission for H. pylori. |
| Databáze: | OpenAIRE |
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