Dosimetric characterization of GMS BT-125-1125I radioactive seed with Monte Carlo simulations and experimental measurement
| Autor: | Ruijie Yang, Li Ren, Jianguo Zhang, Nan Zhao, Junli Li, Yi Fan |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Radioactive seed
Monte Carlo method Analytical chemistry I‐125 radioactive seed 030218 nuclear medicine & medical imaging Iodine Radioisotopes 03 medical and health sciences 0302 clinical medicine Radiation Oncology Physics Humans Dosimetry Computer Simulation Radiology Nuclear Medicine and imaging Radiometry Anisotropy Instrumentation 87.53.?j Monte Carlo simulation Mathematics Radiation Dosimeter dosimetry Phantoms Imaging business.industry Radiotherapy Planning Computer-Assisted Radiotherapy Dosage thermoluminescent dosimeters Monte carlo code 030220 oncology & carcinogenesis Thermoluminescent Dosimetry Radiotherapy Intensity-Modulated Dose rate Nuclear medicine business Monte Carlo Method |
| Zdroj: | Journal of Applied Clinical Medical Physics |
| ISSN: | 1526-9914 |
| DOI: | 10.1002/acm2.12173 |
| Popis: | Purpose To investigate the dosimetric characteristics of the new GMS BT-125-1 125 I radioactive seed, including dose rate constant, radial dose functions, and anisotropy functions. Methods Dosimetric parameters of GMS BT-125-1 125 I seed including dose rate constant, radial dose functions, and anisotropy functions were calculated using the Monte Carlo code of MCNP5, and measured with thermoluminescent dosimeters (TLDs). The results were compared with those of PharmaSeed BT-125-1, PharmaSeed BT-125-2 125 I, and model 6711 125 I seeds. Results The dose rate constant of GMS BT-125-1 125 I seed was 0.959 cGy·h-1·U-1, with the difference of 0.94%, 0.83%, and 0.73% compared with the PharmaSeed BT-125-1 125 I seed, PharmaSeed BT-125-2 125 I seed, and Model 6711 125 I seed, respectively. For radial dose function, the differences between the Monte Carlo and the experimental g(r) results were mostly within 10%. Monte Carlo results of g(r) for GMS BT-125-1 125 I seed were found in agreement (within 3.3%) with corresponding results for the PharmaSeed BT-125-2 125 I seed. The largest differences were 8.1% and 6.2% compared with PharmaSeed BT-125-1 125 I seed and model 6711 125 I seed, respectively. For anisotropy function, the difference between GMS BT-125-1 125 I seed and PharmaSeed BT-125-2 125 I seed was typically Conclusions The measured dose rate constant, radial dose functions, and two-dimensional anisotropy functions for the GMS BT-125-1 125 I seed showed good agreement with the Monte Carlo results. The dose rate constant of the GMS BT-125-1 125 I seed is similar to that of the PharmaSeed BT-125-1 125 I seed, the PharmaSeed BT-125-2 125 I seed, and the model 6711 125 I seed. For radial dose functions and two-dimensional anisotropy functions, the GMS BT-125-1 125 I seed is similar to the PharmaSeed BT-125-2 125 I seed but different from the PharmaSeed BT-125-1 125 I seed and the model 6711 125 I seed. |
| Databáze: | OpenAIRE |
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