Renal tubular acidosis preceding systemic lupus erythematosus
| Autor: | Yogesh Jain, Arvind Bagga, U. N. Bhuyan, Rajendra N. Srivastava |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Nephrology
medicine.medical_specialty Systemic disease Cyclophosphamide Kidney Gastroenterology Renal tubular acidosis Distal renal tubular acidosis Internal medicine medicine Humans Lupus Erythematosus Systemic skin and connective tissue diseases Child Glucocorticoids Acidosis Lupus erythematosus medicine.diagnostic_test business.industry Acidosis Renal Tubular medicine.disease Pediatrics Perinatology and Child Health Immunology Female Renal biopsy medicine.symptom business medicine.drug |
| Zdroj: | Pediatric nephrology (Berlin, Germany). 7(6) |
| ISSN: | 0931-041X |
| Popis: | A 10-year-old girl with distal renal tubular acidosis (RTA) for 4 years (adequately treated for 3 years) developed clinical features suggesting systemic lupus erythematosus (SLE) with supportive laboratory evidence. She had heavy proteinuria and a decreased creatinine clearance (CCr). Renal biopsy showed diffuse proliferative and sclerosing glomerulonephritis with severe tubulointerstitial changes. Following treatment with corticosteroids and cyclophosphamide, she had a clinical remission, an increase in CCr and recovery from systemic acidosis. It is likely that distal RTA in this patient was a manifestation of SLE. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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