Carcinoma of the rete testis: A rare testicular tumor
| Autor: | Tania Platero-Portillo, Diego A. Aguirre, David A. Suarez-Zamora, Mauricio A. Palau-Lazaro, Mauricio Cifuentes-Barreto, Paula A Rodriguez-Urrego |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Male endocrine system Pathology medicine.medical_specialty Pathology and Forensic Medicine 03 medical and health sciences Tunica albuginea (ovaries) 0302 clinical medicine Testicular Neoplasms Rete testis medicine Carcinoma Neoplasm Humans Mesothelioma Rete Testis business.industry Middle Aged medicine.disease Immunohistochemistry Neoplasm Proteins 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Differential diagnosis PAX8 business |
| Zdroj: | Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia. 54(3) |
| ISSN: | 1988-561X |
| Popis: | Carcinoma of the rete testis is a rare malignant tumor which frequently occurs in middle-aged to older patients and has an aggressive biological behavior. We present the case of a 57-year-old man who presented with an ill-defined mass in the right testicle. The patient underwent a radical orchidectomy. Microscopic evaluation showed a neoplasm displaying a complex papillary-cystic architecture, infiltrating the testicular parenchyma. An in situ proliferation of neoplastic cells, with nuclear stratification and scanty cytoplasm was seen at the periphery, within the channels of the rete testis. The tumor infiltrated the tunica albuginea focally without disrupting it completely. Immunohistochemistry was positive for AE1/AE3, CK7, CK34βE12, D2-40, and PAX8. Imaging studies presented no evidence of metastatic disease. These findings are those of a primary rete testis carcinoma. The transition between benign and neoplastic rete testis epithelium served as a helpful diagnostic clue. Metastatic carcinomas from other sites were considered in the differential diagnosis. |
| Databáze: | OpenAIRE |
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