INFLAMMATION-LOWERING EFFECTS OF ORAL ANTIDIABETIC DRUGS IN RHEUMATOID ARTHRITIS

Autor:	Denisa Predeteanu, Ruxandra Ionescu, Madalina Duna, Florian Berghea, Cristina Stoian, Iulia Roman, Bucharest Pharmacy, Maria Magdalena Negru
Rok vydání:	2017
Předmět:	rheumatoid arthritis business.industry oral antidiabetic drugs Inflammation RC581-607 medicine.disease inflammation Rheumatoid arthritis Immunology medicine Medicine General Materials Science Immunologic diseases. Allergy medicine.symptom metformin business
Zdroj:	Romanian Journal of Rheumatology, Vol 26, Iss 1, Pp 17-23 (2017)
ISSN:	2069-6086 1843-0791
Popis:	Objective. The primary aim of this study is to underline the inflammation-lowering effect of oral antidiabetic drugs, namely the CRP, ESR and DAS28 levels. The secondary aim was to show that these effects are dependent on the dose of the antidiabetic drug. Methods. The study has an observational, case-control design. The information was gathered from the case reports of the patients that were admitted in Sf. Maria Clinical Hospital in Bucharest, beginning with 2010 and until May 2016. It included a case group of 20 subjects and a control group of 20 subjects who were followed approximately 3 years from the diagnosis of RA. Results. There were no significant group differences at baseline. During the follow-up, the medians of DAS28, CRP and ESR were significantly lower in the group treated with oral glucose lowering agents (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23da264a0979d74d6e3e2387aeeb588d https://doi.org/10.37897/rjr.2017.1.4 Zobrazit plný text záznamu Plný text ve formátu PDF