Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty
| Autor: | Lamano-Carvalho Tl, S. O. Petenusci, A. A. M. Rosa-E-Silva, Janete Aparecida Anselmo-Franci, S.A. Almeida |
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| Jazyk: | angličtina |
| Rok vydání: | 1998 |
| Předmět: |
Male
LH medicine.medical_specialty endocrine system prolactin Physiology Immunology Biophysics Biology Biochemistry Andrology chemistry.chemical_compound Seminal vesicle Stress Physiological Corticosterone Prepuberty Internal medicine Testis FSH medicine Animals Chronic stress Sexual Maturation Rats Wistar General Pharmacology Toxicology and Pharmaceutics lcsh:QH301-705.5 Testosterone lcsh:R5-920 General Neuroscience Prostate Seminal Vesicles Cell Biology General Medicine Hormones Prolactin spermatogenesis Rats Endocrinology medicine.anatomical_structure chemistry lcsh:Biology (General) immobilization testosterone Androgens Luteinizing hormone lcsh:Medicine (General) Spermatogenesis |
| Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 31, Iss 11, Pp 1443-1448 (1998) Brazilian Journal of Medical and Biological Research, Volume: 31, Issue: 11, Pages: 1443-1448, Published: NOV 1998 Brazilian Journal of Medical and Biological Research v.31 n.11 1998 Brazilian Journal of Medical and Biological Research Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC |
| ISSN: | 0034-7310 |
| Popis: | We investigated whether chronic stress applied from prepuberty to full sexual maturity interferes with spermatogenic and androgenic testicular functions. Male Wistar rats (40 days old) were immobilized 6 h a day for 60 days. Following immobilization, plasma concentrations of corticosterone and prolactin increased 135% and 48%, respectively, while plasma luteinizing hormone and testosterone presented a significant decrease of 29% and 37%, respectively. Plasma concentration of follicle-stimulating hormone was not altered in stressed rats. Chronic stress reduced the amount of mature spermatids in the testis by 16% and the spermatozoon concentration in the cauda epididymidis by 32%. A 17% reduction in weight and a 42% decrease in DNA content were observed in the seminal vesicle of immobilized rats but not in its fructose content. The growth and secretory activity of the ventral prostate were not altered by chronic stress. |
| Databáze: | OpenAIRE |
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