Incidence and clinical characteristics of the infection by the Respiratory Syncytial Virus in children admitted in Santa Casa de São Paulo Hospital
| Autor: | Mirthes Ueda, Edison Luiz Durigon, Saulo Duarte Passos, Maria Carolina Calahani Felicio, Tokiko Kyomen Matsumoto, Rogério Pecchini, Lourdes Rehder de Andrade Vaz de Lima, Maria Cândido O. de Souza, Eitan Naaman Berezin |
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| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Microbiology (medical)
Male medicine.medical_specialty viruses lcsh:QR1-502 Respiratory Syncytial Virus Infections Demographic data Virus lcsh:Microbiology lcsh:Infectious and parasitic diseases Internal medicine Nasopharynx Medicine Humans lcsh:RC109-216 Prospective Studies Respiratory system Respiratory Tract Infections Children business.industry Incidence (epidemiology) Incidence Infant Newborn Infant virus diseases RSV Respiratory infections Mean age Influenza a medicine.disease Virology Hospitalization Infectious Diseases Bronchiolitis Child Preschool Respiratory virus Female Seasons business Brazil |
| Zdroj: | Brazilian Journal of Infectious Diseases v.12 n.6 2008 Brazilian Journal of Infectious Diseases Brazilian Society of Infectious Diseases (BSID) instacron:BSID Brazilian Journal of Infectious Diseases, Vol 12, Iss 6, Pp 476-479 Brazilian Journal of Infectious Diseases, Volume: 12, Issue: 6, Pages: 476-479, Published: DEC 2008 |
| Popis: | The purpose of this study was to identify the rate of infections due to RSV and other viruses in children. In addition we have analyzed demographic data and clinical characteristics of the RSV-positive patients comparing with patients infected by other respiratory viruses. We also described the seasonality of the RSV occurrence in a hospital in São Paulo. Children below 5 years old admitted in Santa Casa de São Paulo Hospital between February 2005 and September 2006 due to acute respiratory infections (ARI) were included. A nasopharyngeal specimens were obtained with sterile No. 5 French feeding catheters as soon as possible (usually within 24 h). Specimens were kept refrigerated at 4 degrees C and transported to Adolfo Lutz Institute, where the indirect immunofluorescent assay was performed. Virus identified by these assay included RSV, Adenovirus, Influenza A and B virus and Parainfluenza 1, 2, and 3. Clinical data from each group was compared. Four hundred and fifty five cases were included in the study, with 30% positive for some type of virus. Viruses that were identified included Respiratory Syncytial Virus (73.03%), Influenza (8.42%), Parainfluenza (8.42%) and Adenovirus (3.37%). We divided the subjects in 3 groups: Group 1 RSV-Positive, Group 2 Other Positive Viruses and Group 3 Negative for Respiratory Virus. Mean age (months) was of 7.5 for RSV-positive children, 7.6 for other viruses, and 8 for negative for respiratory virus. The RSV-Positive Group was significantly younger than the Group Negative for Respiratory Virus (p0.05). Signs of UAI were more present in the Positive RSV Group (p0.05). General mortality was of 2.41%. There was a higher incidence of RSV between the months of March and August in the two years of the study. Our study indicates RSV as the most prevalent viral agent in children admitted due to (ARI), especially in infants below 3 months old. We have also found that infections due to RSV can occur in months others than the classic seasonal period. |
| Databáze: | OpenAIRE |
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