Epithelial-myoepithelial carcinoma of the palate
| Autor: | Minoru Hori, Itaru Moro, Kaoru Kusama, Hiroshi Tanaka, Saito M, Shimizu K, Kozu M |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
Cytoplasm Cancer Research Cell type Pathology medicine.medical_specialty Secretory component Biology Epithelial-myoepithelial carcinoma Epithelium Pathology and Forensic Medicine Keratin medicine Carcinoma Humans Aged chemistry.chemical_classification Palatal Neoplasms S100 Proteins Myoepithelial cell medicine.disease Immunohistochemistry Actins Secretory Component medicine.anatomical_structure Otorhinolaryngology chemistry Keratins Periodontics Muramidase Oral Surgery Cell Division |
| Zdroj: | Journal of Oral Pathology and Medicine. 25:463-466 |
| ISSN: | 1600-0714 0904-2512 |
| DOI: | 10.1111/j.1600-0714.1996.tb00298.x |
| Popis: | A case of epithelial-myoepithelial carcinoma (EMC) of the palate in a 72-year-old Japanese man is described. The patient had noticed swelling of the palate commencing about 20 years previously. Histologically, the tumor consisted of a proliferation of double-layered duct-like structures with two distinctive cell types. The inner layer was composed of eosinophilic epithelial cells, while the outer layer was composed of clear cells. Immunohistochemical analysis revealed that reaction products for total keratin were predominantly found in the cytoplasm of the inner epithelial cells, while those for S-100 protein and smooth muscle actin were observed only in the outer cells. Immunoreactive products for secretory component and lysozyme were found in some of the luminal contents and the inner cells of the tumor nests. These findings indicated this tumor to be an EMC of the palate, which had shown no aggressiveness over a twenty-year period prior to surgical excision. |
| Databáze: | OpenAIRE |
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