Associations between ADIPOQ polymorphisms and coronary artery disease: a meta-analysis
| Autor: | Hongliang Cong, Hong-Yu Zhang, Xia Zhang, Jian Zhang, Yan Jun Cao |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
lcsh:Diseases of the circulatory (Cardiovascular) system Population Coronary Artery Disease 030204 cardiovascular system & hematology Genetic polymorphisms Risk Assessment White People Coronary artery disease 03 medical and health sciences 0302 clinical medicine Asian People Gene Frequency Polymorphism (computer science) Risk Factors Internal medicine medicine Humans Genetic Predisposition to Disease 030212 general & internal medicine Allele education Genetic Association Studies education.field_of_study Polymorphism Genetic Adiponectin business.industry Odds ratio medicine.disease Confidence interval Adiponectin (ADIPOQ) Coronary artery disease (CAD) Meta-analysis Phenotype lcsh:RC666-701 Cardiology and Cardiovascular Medicine business Research Article |
| Zdroj: | BMC Cardiovascular Disorders BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-8 (2019) |
| ISSN: | 1471-2261 |
| Popis: | Background Whether adiponectin (ADIPOQ) polymorphisms are associated with coronary artery disease (CAD) remain controversial. Therefore, we performed this meta-analysis to better explore potential roles of ADIPOQ polymorphisms in CAD. Methods PubMed, Web of Science, Embase and CNKI were searched for eligible studies. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. Results Totally 45 studies were included for pooled analyses. A significant association with the susceptibility to CAD was detected for rs2241766 (dominant model: p = 0.0009, OR = 0.82, 95%CI 0.73–0.92; recessive model: p = 0.04, OR = 1.29, 95%CI 1.02–1.64; allele model: p |
| Databáze: | OpenAIRE |
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