Loss of ATP-dependent lysine uptake in the vacuolar membrane vesicles of Saccharomyces cerevisiae ypq1∆ mutant

Autor:	Nami Murao, Takayuki Sekito, Kyosuke Nakamura, Kunio Manabe, Junichi Tone, Yumika Sato, Yoshimi Kakinuma, Miyuki Kawano-Kawada
Rok vydání:	2014
Předmět:	Saccharomyces cerevisiae Proteins Mutant Lysine Saccharomyces cerevisiae Vacuole Biology Applied Microbiology and Biotechnology Biochemistry Analytical Chemistry chemistry.chemical_compound Adenosine Triphosphate Molecular Biology chemistry.chemical_classification Vesicle Organic Chemistry Membrane Proteins Biological Transport Intracellular Membranes General Medicine biology.organism_classification Cell biology Amino acid Membrane protein chemistry Mutation Vacuoles Adenosine triphosphate Biotechnology
Zdroj:	Bioscience, Biotechnology, and Biochemistry. 78:1199-1202
ISSN:	1347-6947 0916-8451
Popis:	Saccharomyces cerevisiae Ypq1p is a vacuolar membrane protein of the PQ-loop protein family. We found that ATP-dependent uptake activities of amino acids by vacuolar membrane vesicles were impaired by ypq1∆ mutation. Loss of lysine uptake was most remarkable, and the uptake was recovered by overproduction of Ypq1p. Ypq1p is thus involved in transport of amino acids into vacuoles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bad013bb115781750bc4581d62f48f https://doi.org/10.1080/09168451.2014.918489 Zobrazit plný text záznamu