USE OF CYSTATIN C DETERMINATION IN CLINICAL DIAGNOSTICS
| Autor: | Jan Mares, Karel Urbánek, David Stejskal, Jitka Vavrousková, Roman Herzig, Petr Hluštík |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Pathology
medicine.medical_specialty Proteases biology business.industry Renal function urologic and male genital diseases medicine.disease Bioinformatics Cystatins Systemic circulation female genital diseases and pregnancy complications General Biochemistry Genetics and Molecular Biology Clinical Practice Cystatin C Alzheimer Disease Central Nervous System Diseases biology.protein Humans Medicine Dementia Bone Remodeling business Biomarkers |
| Zdroj: | Scopus-Elsevier Europe PubMed Central |
| ISSN: | 1804-7521 1213-8118 |
| DOI: | 10.5507/bp.2003.025 |
| Popis: | This paper presents a current view of the possible clinical uses of cystatin C determination. Cystatin C is an inhibitor of cysteine proteases, and relatively stable in the systemic circulation it is comparatively easily determined. Although in clinical practice it is known primarily as a relatively reliable and endogenous marker for glomerular filtration, lately cystatin C analysis has been discussed in connection with the diagnostics of a variety of diseases such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases. |
| Databáze: | OpenAIRE |
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