Impact of decompressive laminectomy on the functional outcome of patients with metastatic spinal cord compression and neurological impairment
| Autor: | Andreas Unterberg, Klaus Zweckberger, Moritz Scherer, Alexander Younsi, Lennart Riemann |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Decompression
Male Decompressive surgery Cancer Research medicine.medical_specialty Lung Neoplasms medicine.medical_treatment Breast Neoplasms Walking Single Center 03 medical and health sciences 0302 clinical medicine Surgical oncology Prostate Frankel grade Internal medicine Humans Medicine Karnofsky Performance Status Aged Retrospective Studies Spinal Neoplasms Hematology business.industry Laminectomy Prostatic Neoplasms Retrospective cohort study General Medicine Middle Aged medicine.disease Metastatic spinal cord compression (MSCC) Primary tumor Surgery Treatment Outcome medicine.anatomical_structure Spinal metastases Oncology Back Pain 030220 oncology & carcinogenesis Ambulation Female business Spinal Cord Compression 030217 neurology & neurosurgery Progressive disease Research Paper |
| Zdroj: | Clinical & Experimental Metastasis |
| ISSN: | 1573-7276 0262-0898 |
| Popis: | Metastatic spinal cord compression (MSCC) is a frequent phenomenon in advanced tumor diseases with often severe neurological impairments. Affected patients are often treated by decompressive laminectomy. To assess the impact of this procedure on Karnofsky Performance Index (KPI) and Frankel Grade (FG) at discharge, a single center retrospective cohort study of neurologically impaired MSCC-patients treated with decompressive laminectomy between 2004 and 2014 was performed. 101 patients (27 female/74 male; age 66.1 ± 11.5 years) were identified. Prostate was the most common primary tumor site (40%) and progressive disease was present in 74%. At admission, 80% of patients were non-ambulatory (FG A–C). Imaging revealed prevalently thoracic MSCC (78%). Emergency surgery ( |
| Databáze: | OpenAIRE |
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