Magnetic resonance imaging of the endolymphatic space in patients with acute low-tone sensorineural hearing loss
| Autor: | Tadashi Kitahara, Tsuyoshi Sakamoto, Taeko Ito, Hiroshi Inui |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Adolescent Endolymph Hearing Loss Sensorineural Perilymph Young Adult 03 medical and health sciences 0302 clinical medicine Recurrence Vertigo otorhinolaryngologic diseases medicine Humans Endolymphatic Hydrops Inner ear 030223 otorhinolaryngology Glucocorticoids Meniere Disease Aged Aged 80 and over Vestibular system medicine.diagnostic_test biology business.industry Magnetic resonance imaging General Medicine Hearing Loss Sudden Middle Aged Prognosis medicine.disease biology.organism_classification Magnetic Resonance Imaging medicine.anatomical_structure Otorhinolaryngology Ear Inner 030220 oncology & carcinogenesis Vestibule Female Surgery Sensorineural hearing loss sense organs business Nuclear medicine |
| Zdroj: | Auris Nasus Larynx. 46:859-865 |
| ISSN: | 0385-8146 |
| DOI: | 10.1016/j.anl.2019.04.003 |
| Popis: | Objective The aim of this study was to measure the volume of the endolymphatic space (ELS) and to investigate prognosis in patients with acute low-tone sensorineural hearing loss (ALHL). Methods A total of 61 ALHL patients participated; 47 were definite while 14 were probable ALHL cases. The definite ALHL patients were classified into three groups: A, “Cure”; B, “No cure”; and C, “Recurrence.” Also, nine patients for whom diagnosis changed from ALHL to cochlear Meniere’s disease (cMD) without vertigo (ALHL-cMD group). Images of the inner ear fluid space, positive perilymph, and positive endolymph were acquired using a 3T magnetic resonance scanner. Three-dimensional (3D) images were semi-automatically reconstructed using anatomical and tissue information to fuse the 3D images of the inner ear fluid space with the 3D ELS images. Results Patients in the no cure group showed a significantly higher ELS/total fluid space (TFS) volume ratio in the affected cochlear region than the patients of the other groups. Additionally, the affected vestibular ELS/TFS volume ratio in the cure group was significantly lower than that in the recurrence group. There were significantly higher cochlear and vestibular ELS/TFS ratios in ALHL-cMD patients than in control subjects. Conclusions These results indicate that the cochlear ELS/TFS volume ratio should be considered when investigating the extent of recovery, while the extended ELS in the vestibule should be considered when investigating cases of recurrence. Thus, our study suggests that the severe extended ELS appeared likely to change to cMD and that the prognostic determination of ALHL is possible. |
| Databáze: | OpenAIRE |
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