Lethal distemper in badgers (Meles meles) following epidemic in dogs and wolves
| Autor: | Maurilia Marcacci, Fabrizio De Massis, Alessio Lorusso, Daria Di Sabatino, Luca Brugnola, Enzo Ruggieri, Iolanda Mangone, Liana Teodori, Gabriella Di Francesco, Giovanni Savini, Ottavio Portanti, Daniela Malatesta, Pietro Badagliacca, Guendalina Zaccaria |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Microbiology (medical) H protein Lineage (genetic) 040301 veterinary sciences animal diseases Meles Microbiology Virus 0403 veterinary science 03 medical and health sciences Dogs Phylogenetics Genetics medicine Mustelidae Animals Distemper Molecular Biology Distemper Virus Canine Lung Ecology Evolution Behavior and Systematics Phylogeny Wolves biology Canine distemper Histocytochemistry virus diseases 04 agricultural and veterinary sciences Sequence Analysis DNA biology.organism_classification medicine.disease Virology 030104 developmental biology Infectious Diseases Canis RNA Viral Female |
| Zdroj: | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 46 |
| ISSN: | 1567-7257 |
| Popis: | Canine distemper virus (CDV) represents an important conservation threat to many wild carnivores. A large distemper epidemic sustained by an Arctic-lineage strain occurred in Italy in 2013, mainly in the Abruzzi region, causing overt disease in domestic and shepherd dogs, Apennine wolves (Canis lupus) and other wild carnivores. Two badgers were collected by the end of September 2015 in a rural area of the Abruzzi region and were demonstrated to be CDV-positive by real time RT-PCR and IHC in several tissues. The genome of CDV isolates from badgers showed Y549H substitution in the mature H protein. By employing all publicly available Arctic-lineage H protein encoding gene sequences, six amino acid changes in recent Italian strains with respect to Italian strains of dogs from 2000 to 2008, were observed. A CDV strain belonging to the European-wildlife lineage was also identified in a fox found dead in the same region in 2016, proving co-circulation of an additional CDV lineage. |
| Databáze: | OpenAIRE |
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