Surgical wound debridement sequentially characterized in a porcine burn model with multispectral imaging
| Autor: | Wensheng Fan, John J. Squiers, Jeffrey E. Thatcher, Eric W. Sellke, Weirong Mo, Weizhi Li, Darlene R. King, Rachit Mohan, Xu Zhang, J. Michael DiMaio |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Wound site medicine.medical_specialty Swine medicine.medical_treatment Multispectral image Healthy tissue Critical Care and Intensive Care Medicine Image Processing Computer-Assisted Medical imaging medicine Animals Absorbance spectra Wound Healing Debridement business.industry Spectrum Analysis Surgical wound General Medicine Surgery Disease Models Animal Emergency Medicine Burns Nuclear medicine business Partial thickness |
| Zdroj: | Burns. 41:1478-1487 |
| ISSN: | 0305-4179 |
| DOI: | 10.1016/j.burns.2015.05.009 |
| Popis: | Introduction Multispectral imaging (MSI) is an optical technique that measures specific wavelengths of light reflected from wound site tissue to determine the severity of burn wounds. A rapid MSI device to measure burn depth and guide debridement will improve clinical decision making and diagnoses. Methodology We used a porcine burn model to study partial thickness burns of varying severity. We made eight 4 × 4 cm burns on the dorsum of one minipig. Four burns were studied intact, and four burns underwent serial tangential excision. We imaged the burn sites with 400–1000 nm wavelengths. Results Histology confirmed that we achieved various partial thickness burns. Analysis of spectral images show that MSI detects significant variations in the spectral profiles of healthy tissue, superficial partial thickness burns, and deep partial thickness burns. The absorbance spectra of 515, 542, 629, and 669 nm were the most accurate in distinguishing superficial from deep partial thickness burns, while the absorbance spectra of 972 nm was the most accurate in guiding the debridement process. Conclusion The ability to distinguish between partial thickness burns of varying severity to assess whether a patient requires surgery could be improved with an MSI device in a clinical setting. |
| Databáze: | OpenAIRE |
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