The effects of cardiac resynchronization therapy on left ventricular and mitral valve geometry and secondary mitral regurgitation in patients with left bundle branch block

Autor:	Gaurav A. Upadhyay, Orlando Santana, Mary Orencole, Michael H. Picard, Jagmeet P. Singh, Christos G. Mihos, Romain Capoulade, Evin Yucel
Rok vydání:	2019
Předmět:	Male Heart Ventricles medicine.medical_treatment Bundle-Branch Block Cardiac resynchronization therapy Geometry 030204 cardiovascular system & hematology Severity of Illness Index Ventricular Function Left Cardiac Resynchronization Therapy 03 medical and health sciences QRS complex 0302 clinical medicine Mitral valve medicine Humans Radiology Nuclear Medicine and imaging In patient 030212 general & internal medicine Aged Retrospective Studies Mitral regurgitation Ejection fraction Ventricular Remodeling business.industry Left bundle branch block Mitral Valve Insufficiency Repeated measures design medicine.disease Treatment Outcome medicine.anatomical_structure Echocardiography Mitral Valve Female Cardiology and Cardiovascular Medicine business Follow-Up Studies
Zdroj:	Echocardiography. 36:1450-1458
ISSN:	1540-8175 0742-2822
DOI:	10.1111/echo.14444
Popis:	BACKGROUND Secondary mitral regurgitation (MR) is common in patients with left bundle branch block (LBBB) undergoing cardiac resynchronization therapy (CRT). We aimed to define CRT effects on left ventricular (LV) and mitral valve (MV) geometry, and their correlation with MR severity. METHODS Forty-one patients with LBBB and ≥mild secondary MR underwent CRT between 2009 and 2012, and had baseline and follow-up echocardiograms available. Repeated measure and linear regression analyses were performed to assess for changes in MV and LV geometry and MR severity, and associations with follow-up MR grade. RESULTS The mean age and baseline QRS duration were 65.5 ± 14.9 years and 160 ± 24 ms. At a mean follow-up of 2.6 ± 1.8 years, there was an increase in LV ejection fraction and reductions in LV end-systolic volume index, MR grade, and end-systolic interpapillary muscle distance (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2395a8c4045566bdd447e3d6d107a17a https://doi.org/10.1111/echo.14444 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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