Does mammographic density remain a radiological challenge in the digital era?
| Autor: | Rula AbuTaimai, Mohammad Rawashdeh, Dana S Al-Mousa, Kelly Spuur, Patrick C. Brennan, Maram Alakhras |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Digital mammography Digital era Breast Neoplasms Cancer detection Sensitivity and Specificity Breast cancer medicine Humans Radiology Nuclear Medicine and imaging Breast Aged Breast Density Jordan Radiological and Ultrasound Technology business.industry MAMMOGRAPHIC DENSITY Reproducibility of Results General Medicine Middle Aged Fibroglandular Tissue medicine.disease Mammographic breast density Radiological weapon Clinical Competence Radiology business Mammography |
| Zdroj: | Acta Radiologica. 62:707-714 |
| ISSN: | 1600-0455 0284-1851 |
| Popis: | Background The low subject contrast between cancerous and fibroglandular tissue could obscure breast abnormalities. Purpose To investigate radiologists’ performance for detection of breast cancer in low and high mammographic density (MD) when cases are digitally acquired. Material and Methods A test set of 60 digital mammography cases, of which 20 were cancerous, were examined by 17 radiologists. Mammograms were categorized as low (≤50%) or high (>50%) MD and rated for suspicion of malignancy using the Royal Australian and New Zealand College of Radiology (RANZCR) classification system. Radiologist demographics including cases read per year, age, subspecialty, and years of reporting were recorded. Radiologist performance was analyzed by the following metrics: sensitivity; specificity; area under the receiver operating characteristic (ROC) curve (AUC), location sensitivity, and jackknife free-response ROC (JAFROC) figure of merit (FOM). Results Comparing high to low MD cases, radiologists showed a significantly higher sensitivity ( P = 0.015), AUC ( P = 0.003), location sensitivity ( P = 0.002), and JAFROC FOM ( P = 0.001). In high compared to low MD cases, radiologists with Conclusion In this experimental situation, radiologists’ performance was higher when reading cases with high compared to low MD. Experienced radiologists were able to precisely localize lesions in breasts with higher MD. Further studies in unselected screening materials are needed to verify the results. |
| Databáze: | OpenAIRE |
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