Ascorbic Acid Biosyntheses After Phenobarbital in Male and Female Rats
| Autor: | Teague Rs, McKernan Jb |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Male
medicine.medical_specialty Gulonolactone hydrolase Alcohol oxidoreductase Ascorbic Acid General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Sex Factors Internal medicine Hydrolase medicine Animals Humans Glucuronolactone chemistry.chemical_classification biology Esterases Ascorbic acid Enzyme assay Rats Alcohol Oxidoreductases Enzyme Endocrinology Liver chemistry Biochemistry Phenobarbital biology.protein Female medicine.drug |
| Zdroj: | Experimental Biology and Medicine. 143:340-342 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-143-37316 |
| Popis: | SummaryMale and female rats were treated for 5 days with phenobarbital and the four hepatic enzymes in the ascorbic acid pathway were assayed. In males, gulonate NADP-oxidoreductase were found to have decreased enzyme activity while glucuronolactone hydrolase activity remained unchanged. In females, gulonolactone hydrolase and gulonolactone-O2-oxidoreductase had decreased enzyme activity, gulonate-NADP-oxidoreductase remained unchanged while glucuronolactone hydrolase was found to have increased twofold in activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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