| Popis: |
Figure S7. Inhibition of monocarboxylate transporters regulates intracellular and extracellular lactate. Western blot shows expression of MCT4 in monocultures of MCF7, T47D, HS5, and HS27a cells. Images are from adjacent lanes on one gel and non-adjacent lanes from a second gel. We show β-actin as a loading control. B,C) Graphs show mean values ± standard deviation for relative concentrations of intracellular (B) and extracellular (C) lactate in monocultures of MCF7 cells or co-cultures of MCF7 and HS5 cells treated with 10 µM syrosingopine, an inhibitor of MCT1/4, or vehicle for 3 days. *** p |
