Antiphospholipid antibodies in pediatrics
| Autor: | Ana I. Quintero-Del-Rio |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Hemolytic anemia
medicine.medical_specialty Enzyme-Linked Immunosorbent Assay Gastroenterology Rheumatology immune system diseases Antiphospholipid syndrome Pregnancy Internal medicine medicine Beta 2-Glycoprotein I Humans skin and connective tissue diseases Child Livedo reticularis Glycoproteins Lupus anticoagulant Aspirin business.industry Pregnancy Outcome Anticoagulants Thrombosis Heparin Heparin Low-Molecular-Weight medicine.disease Antiphospholipid Syndrome Pregnancy Complications beta 2-Glycoprotein I Lupus Coagulation Inhibitor Antibodies Antiphospholipid Female medicine.symptom business medicine.drug |
| Zdroj: | Current rheumatology reports. 4(5) |
| ISSN: | 1523-3774 |
| Popis: | Antiphospholipid antibody syndrome has been associated with vascular thrombosis, thrombocytopenia, hemolytic anemia, livedo reticularis, neurologic disorders, and recurrent fetal loss. The diagnosis of antiphospholipid syndrome is given in the presence of an elevated anticardiolipin antibody lupus anticoagulant in addition to a thrombotic event. Antiphospholipid antibodies are responsible for a majority of thrombotic events in children. These antibodies can present as a primary syndrome or secondary to other diseases, such as systemic lupus erythematosus. Anticoagulation therapy with heparin and low-dose aspirin is the recommended treatment in pediatric patients. |
| Databáze: | OpenAIRE |
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