Lipid Profile and Impulsivity in Suicidal Patients with Major Depressive Disorder
Autor: | Mohamed Hossam EL-Din Abd el moneam, Nermin M. Shaker, MarwaAbdelrahman Sultan, Mohamed Youssef Mohamed, Sara Abdallah Helal |
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Rok vydání: | 2020 |
Předmět: |
050103 clinical psychology
medicine.medical_specialty Suicide Attempted Impulsivity Suicidal Ideation 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans 0501 psychology and cognitive sciences Suicidal patients Depressive Disorder Major medicine.diagnostic_test Serum lipid levels business.industry 05 social sciences medicine.disease Lipids 030227 psychiatry Psychiatry and Mental health Clinical Psychology Impulsive Behavior Major depressive disorder lipids (amino acids peptides and proteins) Observational study medicine.symptom Lipid profile business Cohort study |
Zdroj: | Archives of Suicide Research. 25:641-656 |
ISSN: | 1543-6136 1381-1118 |
DOI: | 10.1080/13811118.2020.1746456 |
Popis: | Previous observational cohort studies showed an association between low serum lipid levels and suicide. This study was undertaken to examine the relationship between lipid parameters and impulsivity in suicidal patients with major depressive disorder (MDD).The current study included 100 patients with MDD distributed as 50 patients with recent suicidal attempts and 50 patients with no lifetime history of suicide. Participants were subjected to Structured Clinical Interview for DSM-IV Axis I Disorders (SCID I) to confirm the diagnosis. The risk of suicide was assessed through the Suicide Probability Scale (SPS), while the intent and seriousness of suicide were assessed through Beck's Suicidal Intent Scale. assessment of impulsivity was carried out through Barratt Impulsivity Scale. Serum lipid levels were measured in mg/dL after an overnight fast.Total cholesterol (TC) was found significantly lower in the suicidal group compared to the non-suicidal depressed group (Low TC and LDL could predict suicidal behavior in patients with MDD. Impulsivity could not be a mediator or predictor of suicide risk in patients with MDD. |
Databáze: | OpenAIRE |
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