| Popis: |
Coronavirus disease-19 (COVID-19) which is an enveloped RNA beta coronavirus. First emerged in December 2019 in China and rapidly spread worldwide. Although various studies have reported that COVID-19 is associated with a hypercoagulable state and thrombotic complications in critically ill patients. The current SARS-CoV-2 pandemic is causing high morbidity and mortality, its main affectation is at the pulmonary level, however, the virus also affects the cardiovascular system. The vasculature is affected directly by the virus and indirectly by a storm of inflammatory cytokines, causing an excessive inflammatory process, platelet activation, endothelial dysfunction and stasis. Biochemically it manifests itself with altered coagulation parameters, increased levels of D-dimer and Ferritin, which are the most common laboratory abnormalities related to mortality. In our investigation, acroischemic lesions were found in critically ill patients with severe limb ischemia. |
