Serum cortisol concentration with exploratory cut-off values do not predict the effects of hydrocortisone administration in children with low cardiac output after cardiac surgery
| Autor: | Karin Hogenbirk, Arno Roest, Ronald van Brempt, Mark G. Hazekamp, E.J. Verweij, Evert de Jonge |
|---|---|
| Přispěvatelé: | Cardiothoracic Surgery, Other departments |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Pulmonary and Respiratory Medicine
Inotrope Heart Defects Congenital Male medicine.medical_specialty Cardiac output Cardiotonic Agents Time Factors Hydrocortisone Cardiac Output Low Hemodynamics Urination Blood Pressure Cortisol Internal medicine Adrenal insufficiency medicine Humans Vasoconstrictor Agents Lactic Acid Low cardiac output syndrome Cardiac Surgical Procedures Child Retrospective Studies business.industry Patient Selection Age Factors Infant Newborn Infant Original Articles medicine.disease Cardiac surgery Endocrinology Blood pressure Treatment Outcome Anesthesia Child Preschool Surgery Female Cardiology and Cardiovascular Medicine business Biomarkers Paediatric cardiac surgery medicine.drug Adrenal Insufficiency |
| Zdroj: | Interactive cardiovascular and thoracic surgery, 15(4), 685-689. Oxford University Press Interactive Cardiovascular and Thoracic Surgery, 15(4), 685-689 |
| ISSN: | 1569-9285 |
| Popis: | OBJECTIVES: Low cardiac output syndrome is common after paediatric cardiac surgery. Previous studies suggested that hydrocortisone administration may improve haemodynamic stability in case of resistant low cardiac output syndrome in critically ill children. This study was set up to test the hypothesis that the effects of hydrocortisone on haemodynamics in children with low cardiac output syndrome depend on the presence of (relative) adrenal insufficiency. METHODS: A retrospective study was done on paediatric patients who received hydrocortisone when diagnosed with resistant low cardiac output syndrome after paediatric cardiac surgery in the period from 1 November 2005 to 31 December 2008. We studied the difference in effects of treatment with hydrocortisone administration between patients with adrenal insufficiency defined as an exploratory cut-off value of total cortisol of |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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