Non-Traumatic Intracerebral Hematoma in the Young: Findings from a Tertiary Hospital in the Philippines
| Autor: | Gerard Eastdon Truadio Dales Ochoco, Jose Danilo B. Diestro, Julian Spears, Abdelsimar T. Omar, Jose Miguel M. Medrano, Maria Carissa C. Pineda-Franks, Kathleen Joy O. Khu, Clare Angeli G. Enriquez |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Intracranial Arteriovenous Malformations Male Pediatrics medicine.medical_specialty Philippines Logistic regression Tertiary Care Centers 03 medical and health sciences Young Adult 0302 clinical medicine Hematoma Age Distribution Risk Factors Non traumatic medicine Humans Cerebral Hemorrhage Retrospective Studies business.industry Incidence (epidemiology) Incidence Rehabilitation Retrospective cohort study Intracranial Aneurysm Middle Aged medicine.disease Prognosis Intracerebral hematoma Cohort Hypertension Etiology Surgery Female Neurology (clinical) Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 29(11) |
| ISSN: | 1532-8511 |
| Popis: | Background There is geographic variability in the clinical profile and outcomes of non-traumatic intracerebral hematoma (ICH) in the young, and data for the Philippines is lacking. We aimed to describe this in a cohort from the Philippines, and identify predictors of mortality. Methods We performed a retrospective study of all patients aged 19–49 years with radiographic evidence of non-traumatic ICH admitted in our institution over five years. Data on demographics, risk factors, imaging, etiologies, surgical management, in-hospital mortality, and discharge functional outcomes were collected. Multivariate logistic regression analysis was done to determine factors predictive of mortality. Results A total of 185 patients were included, which had a mean age of 40.98 years and a male predilection (71.9%). The most common hematoma location was subcortical, but it was lobar for the subgroup of patients aged 19-29 years. Overall, the most common etiology was hypertension (73.0%), especially in patients aged 40-49. Conversely, the incidence of vascular lesions and thrombocytopenia was higher in patients aged 19-29. Surgery was done in 7.0% of patients. The rates of mortality and favorable functional outcome at discharge were 8.7% and 35.1%, respectively. Younger age (p = 0.004), higher NIHSS score on admission (p=0.01), higher capillary blood glucose on admission (p=0.02), and intraventricular extension of hematoma (p = 0.01) predicted mortality. Conclusions In the Philippines, the most common etiology of ICH in young patients was hypertension, while aneurysms and AVM's were the most common etiology in the subgroup aged 19 – 29 years. Independent predictors of mortality were identified. |
| Databáze: | OpenAIRE |
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