Paradoxical embolism causing stroke and migraine
Autor: | G S Ray, S Nightingale |
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Rok vydání: | 2010 |
Předmět: |
Adult
medicine.medical_specialty Right-to-left shunt Migraine with Aura Foramen Ovale Patent Paradoxical embolism medicine.artery Internal medicine medicine Humans Stroke business.industry Angiography General Medicine Prostheses and Implants medicine.disease Thrombosis Embolization Therapeutic Migraine with aura Surgery Treatment Outcome Embolism Migraine Echocardiography Patent foramen ovale Cardiology Female Telangiectasia Hereditary Hemorrhagic medicine.symptom business Embolism Paradoxical |
Zdroj: | Journal of postgraduate medicine. 56(3) |
ISSN: | 0972-2823 |
Popis: | This case report describes a lady who underwent investigations as a part of a clinical study. A 32-year-old woman with a history of episodes of severe migraine with aura, deep vein thrombosis and recurrent epistaxis, presented with two episodes of stroke with no particular cause evident on routine investigations. A contrast echocardiogram demonstrated a patent foramen ovale (PFO). She was found to be positive for the Factor V Leiden mutation. The PFO was closed percutaneously. However, a substantial right to left shunt of 14% persisted. Pulmonary angiography revealed multiple arterio-venous malformations (AVMs) and she was diagnosed with hereditary hemorrhagic telangiectasia. The AVMs were embolized and she has had no further cerebral events. Interestingly, her episodes of 'migraine' have also improved dramatically following the closure of the PFO and the embolization of the AVMs. This case demonstrates the complex relationship between right to left shunts, cryptogenic stroke and migraine. |
Databáze: | OpenAIRE |
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