Additional file 1 of The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation

Autor: Morrissey, Maria E., Róisín Byrne, Nulty, Celina, McCabe, Niamh H., Lynam-Lennon, Niamh, Butler, Clare T., Kennedy, Susan, O’Toole, Dermot, Larkin, John, McCormick, Paul, Mehigan, Brian, Mary-Clare Cathcart, Lysaght, Joanne, Reynolds, John V., Ryan, Elizabeth J., Dunne, Margaret R., O’Sullivan, Jacintha
Rok vydání: 2020
DOI: 10.6084/m9.figshare.12502370.v1
Popis: Additional file 1 Supplementary Table 1. Patient demographics. Supplementary Fig. 1. Experimental outline and flow cytometry gating strategy and staining controls. Supplementary Fig. 2. ex vivo TCM from distinct gastrointestinal adenocarcinoma types induced differential effects on LPS-induced DC maturation. Supplementary Fig. 3. ex vivo TCM from distinct gastrointestinal adenocarcinoma types induced differential effects on unstimulated DC marker levels. Supplementary Fig. 4. in vitro TCM of 2Gy-irradiated cell lines from gastrointestinal cancers induced significant inhibition of DC markers compared to mock irradiation. Supplementary Fig. 5. ex vivo TCM of 2Gy-irradiated TME from gastrointestinal cancers inhibited DC markers compared to mock irradiation
Databáze: OpenAIRE