Osseointegrating and phase-oriented micro-arc-oxidized titanium dioxide bone implants
| Autor: | Chih-Hsin Tang, Ju-Liang He, Hsien-Te Chen, Chi-Jen Chung, Hsin-I Lin |
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| Rok vydání: | 2021 |
| Předmět: |
Materials science
Surface Properties Biomedical Engineering Biophysics Bioengineering 02 engineering and technology Osseointegration Biomaterials chemistry.chemical_compound Coated Materials Biocompatible Phase (matter) Shear strength Cell adhesion Titanium Arc (protein) 020502 materials Bone implant technology industry and agriculture General Medicine Active surface 021001 nanoscience & nanotechnology 0205 materials engineering chemistry Titanium dioxide 0210 nano-technology TP248.13-248.65 Biomedical engineering Biotechnology |
| Zdroj: | Journal of Applied Biomaterials & Functional Materials, Vol 19 (2021) |
| ISSN: | 2280-8000 |
| Popis: | Here, we present a bone implant system of phase-oriented titanium dioxide (TiO2) fabricated by the micro-arc oxidation method (MAO) on β-Ti to facilitate improved osseointegration. This (101) rutile-phase-dominant MAO TiO2 (R-TiO2) is biocompatible due to its high surface roughness, bone-mimetic structure, and preferential crystalline orientation. Furthermore, (101) R-TiO2 possesses active and abundant hydroxyl groups that play a significant role in enhancing hydroxyapatite formation and cell adhesion and promote cell activity leading to osseointegration. The implants had been elicited their favorable cellular behavior in vitro in the previous publications; in addition, they exhibit excellent shear strength and promote bone–implant contact, osteogenesis, and tissue formation in vivo. Hence, it can be concluded that this MAO R-TiO2 bone implant system provides a favorable active surface for efficient osseointegration and is suitable for clinical applications. |
| Databáze: | OpenAIRE |
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