Dialkylamino cyclopentadienyl ruthenium(ii ) complex-catalyzed α-alkylation of arylacetonitriles with primary alcohols
| Autor: | Wenxu Zheng, Hung Wai Cheung, Zhenyang Lin, Chak Po Lau, Juan Li, Yu Hin Chiu, Zhongyuan Zhou |
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| Rok vydání: | 2010 |
| Předmět: |
Models
Molecular Acetonitriles Magnetic Resonance Spectroscopy Alkylation Chemistry Ligand Hydride chemistry.chemical_element Protonation Hydrocarbons Aromatic Medicinal chemistry Catalysis Ruthenium Inorganic Chemistry Metal Cyclopentadienyl complex Alcohols visual_art visual_art.visual_art_medium Ruthenium Compounds Organic chemistry |
| Zdroj: | Dalton Trans.. 39:265-274 |
| ISSN: | 1477-9234 1477-9226 |
| DOI: | 10.1039/b917805h |
| Popis: | Aminocyclopentadienyl ruthenium complexes, [(eta(5)-C(5)H(4)NMe(2))Ru(PPh(3))(2)(CH(3)CN)](+)BF(4)(-) and [(eta(5)-C(5)H(4)NEt(2))Ru(PPh(3))(2)(CH(3)CN)](+)BF(4)(-), are moderately active catalysts for alpha-alkylation of arylacetonitriles with primary alcohols; on the other hand, the analogous unsubstituted cyclopentadienyl ruthenium complex [(eta(5)-C(5)H(5))Ru(PPh(3))(2)(CH(3)CN)](+)BF(4)(-) shows very low catalytic activity. On the basis of experimental results and theoretical calculations, rationalization for the much higher catalytic activity of the aminocyclopentadienyl complexes over that of the unsubstituted Cp complex is provided. In the catalytic systems with the former, it is possible to regenerate the active solvento complexes via protonation of the metal hydride intermediates and subsequent ligand substitution; this process is, however, very nonfacile in the catalytic system with the latter. |
| Databáze: | OpenAIRE |
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