Plasma concentrations of vitamin D metabolites in pubertal girls with anorexia nervosa

Autor: Dagfinn Aarskog, T. Markestad, O. Trygstad, Lage Aksnes
Rok vydání: 1986
Předmět:
Zdroj: Acta Endocrinologica. 113:S458-S467
ISSN: 1479-683X
0804-4643
DOI: 10.1530/acta.0.112s458
Popis: Plasma concentrations of 25-hydroxyvitamin D (25-OHD), 1,25-dihydroxyvitamin D (1,25-(OH)2D), 24,25-dihydroxyvitamin D (24,25-(OH)2D) and vitamin D-binding protein (DBP) were measured in 12 pubertal girls (aged 10-18 yr) with anorexia nervosa in relapse. The results were compared with similar data obtained in 81 healthy girls representing all stages of puberty. The patients with anorexia nervosa had significantly lower 1,25-(OH)2D levels (71 vs. 124 pmol/l; p2D levels (6.0 vs. 3.2 nmol/l; p2D to 25-OHD, which reflects the relative activity of the 24-hydroxylation, were significantly higher in the anorectics (6.6 % vs. 3.6 %; p2 D" was significantly lower in the anorectic patients (p2D and increase of the 24,25-(OH)2D concentration. Key words: Anorexia nervosa, vitamin D metabolism, 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, 24,25-dihydroxyvitamin D, vitamin D binding protein
Databáze: OpenAIRE