INCREASED APOTRANSCOBALAMIN II LEVELS IN RHEUMATOID ARTHRITIS
| Autor: | S. Benito-Urbina, E. De Miguel, José Juan Vázquez, José Peña, A. F. Zamorano, Francisco Arnalich, J. Gijón-Baños |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male medicine.medical_specialty Endogeny Cobalamin Arthritis Rheumatoid chemistry.chemical_compound Rheumatology Internal medicine polycyclic compounds medicine Humans Distribution (pharmacology) Pharmacology (medical) Clinical significance In patient Cyanocobalamin Aged Transcobalamins business.industry Osmolar Concentration Middle Aged medicine.disease Immune complex Vitamin B 12 Endocrinology chemistry Rheumatoid arthritis Female business |
| Zdroj: | Rheumatology. 29:171-173 |
| ISSN: | 1462-0332 1462-0324 |
| DOI: | 10.1093/rheumatology/29.3.171 |
| Popis: | The distribution of endogenous cobalamin among serum cobalamin-binding proteins was studied in 30 patients with active rheumatoid arthritis (RA) and 27 in clinical remission. The mean total serum cobalamin concentration (holo-transcobalamin I and II) was similar in both groups of patients, whereas mean apotranscobalamin II was significantly increased in patients with active RA. The clinical significance of this finding is not yet established but it might be a useful parameter for the evaluation of disease activity in RA. |
| Databáze: | OpenAIRE |
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