Misoprostol in Addition to a Double-Balloon Catheter for Induction: A Double-Blind Randomized Controlled Trial
| Autor: | Wei-Hsuan Lo-Ciganic, Maritza G. Gonzalez, Meghan G. Hill, Kathryn L. Reed |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors Placebo Catheterization law.invention Young Adult 03 medical and health sciences 0302 clinical medicine Double-Blind Method Randomized controlled trial Pregnancy law Oxytocics medicine Humans Labor Induced 030212 general & internal medicine Misoprostol 030219 obstetrics & reproductive medicine Cesarean Section Vaginal delivery business.industry Obstetrics and Gynecology medicine.disease Combined Modality Therapy Surgery Double balloon catheter Administration Intravaginal Catheter Logistic Models Oxytocin Anesthesia Pediatrics Perinatology and Child Health Female business Cervical Ripening medicine.drug |
| Zdroj: | American Journal of Perinatology. 35:225-232 |
| ISSN: | 1098-8785 0735-1631 |
| Popis: | Objective This article aims to evaluate whether the use of a double-balloon catheter with oral misoprostol results in a lower rate of cesarean and shorter times to delivery than the use of the double-balloon catheter with oral placebo. Study Design In a double-blind randomized controlled trial, a double-balloon catheter was used for induction of labor with two doses of either 50 µg of misoprostol or placebo. Outcomes included cesarean rate, time to vaginal delivery, change in Bishop's score, and oxytocin usage. Results A total of 343 women were screened and 199 randomized: 99 to the misoprostol arm and 100 to the placebo arm. Cesarean delivery rate was not different between the groups (misoprostol: 13.1% vs. placebo: 17.0%, p = 0.45). Time to vaginal delivery was significantly shorter (mean: 14.6 ± 6.9 vs. 20.8 ± 13.8 hours, p Conclusion The use of a double-balloon catheter with oral misoprostol for induction did not reduce the cesarean delivery rate, but did result in shorter labors, a greater increase in Bishop's score, and a lower need for oxytocin use. |
| Databáze: | OpenAIRE |
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