Mycobacterium marinum: nodular hand lesions after a fishing expedition
| Autor: | Onyema Ogbuagu, Anne Spichler-Moffarah, Jessica Tuan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Tenosynovitis biology business.industry Osteomyelitis Soft tissue Case Report General Medicine 030105 genetics & heredity bacterial infections and mycoses medicine.disease biology.organism_classification Dermatology 03 medical and health sciences 0302 clinical medicine Clarithromycin medicine Disseminated disease business 030217 neurology & neurosurgery Rifampicin Ethambutol Mycobacterium marinum medicine.drug |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| Popis: | Mycobacterium marinum is a slow-growing, acid-fast bacillus in the category of non-tuberculous mycobacteria which most commonly cause skin and soft tissue infections in patients, particularly those with aquatic exposure. Classically, M. marinum skin and soft tissue infections clinically manifest with formation of nodular or sporotrichoid extremity lesions, or deeper space infections such as tenosynovitis and osteomyelitis. Disseminated disease may occur in immunocompromised hosts. M. marinum is a slow-growing organism that is challenging to culture, as it typically requires 5–14 days (yet may take up to several weeks) with low temperatures of approximately 30°C to yield growth. In terms of treatment, further data are needed to elucidate the optimal regimen and duration for M. marinum infections. Combination therapy with clarithromycin and ethambutol is recommended for treatment of skin and soft tissue infections, with addition of rifampicin for deeper space infections. Surgery may be needed in addition to medical management. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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