The anisotropic network model web server at 2015 (ANM 2.0)
| Autor: | Gengkon Lum, Eran Eyal, Ivet Bahar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Statistics and Probability
Web server Anisotropic Network Model Computer science Protein Conformation Distributed computing computer.software_genre Ligands Biochemistry 03 medical and health sciences Motion 0302 clinical medicine Software Molecular Biology Simulation 030304 developmental biology Network model Flexibility (engineering) 0303 health sciences Internet business.industry Proteins RNA-Binding Proteins DNA Applications Notes Structural Bioinformatics Computer Science Applications DNA metabolism DNA-Binding Proteins Computational Mathematics Computational Theory and Mathematics Anisotropy RNA The Internet business computer 030217 neurology & neurosurgery |
| Zdroj: | Bioinformatics |
| ISSN: | 1367-4811 1367-4803 |
| Popis: | Summary: The anisotropic network model (ANM) is one of the simplest yet powerful tools for exploring protein dynamics. Its main utility is to predict and visualize the collective motions of large complexes and assemblies near their equilibrium structures. The ANM server, introduced by us in 2006 helped making this tool more accessible to non-sophisticated users. We now provide a new version (ANM 2.0), which allows inclusion of nucleic acids and ligands in the network model and thus enables the investigation of the collective motions of protein–DNA/RNA and –ligand systems. The new version offers the flexibility of defining the system nodes and the interaction types and cutoffs. It also includes extensive improvements in hardware, software and graphical interfaces. Availability and implementation: ANM 2.0 is available at http://anm.csb.pitt.edu Contact: eran.eyal@sheba.health.gov.il, eyal.eran@gmail.com |
| Databáze: | OpenAIRE |
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