Excimer–monomer fluorescence changes by supramolecular disassembly for protein sensing and quantification
| Autor: | Jenna Westley, Sankaran Thayumanavan, Hongxu Liu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Macromolecular Substances
Supramolecular chemistry Ligands Photochemistry Excimer Fluorescence Article Catalysis Dissociation (chemistry) chemistry.chemical_compound Interference (communication) Materials Chemistry Fluorescent Dyes Molecular Structure Metals and Alloys Proteins A protein General Chemistry Surfaces Coatings and Films Electronic Optical and Magnetic Materials Spectrometry Fluorescence Monomer chemistry Ceramics and Composites Selectivity |
| Zdroj: | Chem Commun (Camb) |
| ISSN: | 1364-548X 1359-7345 |
| Popis: | A protein binding-induced supramolecular dissociation strategy is developed with the ratio of monomer and excimer fluorescence as the tool for protein sensing and quantification. Due to the “lock-and-key” strategy based on specific ligand-protein binding, the probe exhibits excellent selectivity and quantification accuracy to the protein of interest. The ratiometric approach is immune to interference from extrinsic quenchers, while preserving the opportunity to be protein specific. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|